Dillon Gabriel will try to win his first NFL game when the Cleveland Browns go on the road to take on the Pittsburgh Steelers on Sunday.

Gabriel and the Browns nearly stole a win from their trip to London before giving up a late touchdown in their 24-21 loss to the Minnesota Vikings.

Cleveland (1-4) is a solid underdog Sunday at Pittsburgh, but not as big as some would think, given the battle between first- and last-place teams.

Here’s a look at the betting lines at the best Ohio sportsbooks and how to bet on Browns Week 6 odds for their game against the Steelers.

Browns vs Steelers predictions and best bets

• Steelers -5.5: (-105) at DraftKings
• Under 38.5 points: (-110) at BetMGM
• Browns team total Under 17.5: (-155) at FanDuel

The Steelers are 0-1 at Acrisure Stadium, and their defense has been an issue during their 3-1 start. Yet, T.J. Watt and Cam Heyward came alive in the Steelers’ win over the Vikings in Dublin, Ireland, and Gabriel may have a hard time escaping that duo.

The Browns’ defense has also been great. Cleveland has given up the second-fewest yards per game (247.8) and is fifth in the league in sacks (14). The Browns should get after Pittsburgh QB Aaron Rodgers and make life hectic.

If the Steelers’ defense has its mojo back, it shouldn’t take that many points for Pittsburgh to cover the spread. This is especially true, since Cleveland averages 16 points per game over its past four trips to Western Pennsylvania and is 0-4 since winning 48-37 in the 2020 Wild Card Round.

Plus, the Steelers had a bye after their trip to Europe, but the Browns did not. They may tire more easily than their counterparts, especially on defense.

*Note: Odds are based on the best value our experts find as of publication; check lines closer to game time to ensure you get the best odds.

Browns vs Steelers moneyline analysis

The Browns have lost 11 games away from Huntington Bank Stadium and 10 straight true road games. They are 1-10 in their past 11 games dating back to the Jameis Winston-led 24-19 win over the Steelers on Thursday Night Football in the snow last November.

Yet, somehow, Pittsburgh, and its minus-2 point differential, is only a -275 moneyline favorite. The Steelers have roughly a 73.3% implied probability of winning the game, based on the odds, yet that still seems low, based on Gabriel playing on the road in a divisional affair.

The Steelers do have three wins in one-possession games, and two wins by three points or fewer. So if pressed to pick a team to win outright in a battle of these rivals, it’s hard to bet against Pittsburgh.

Why the Steelers could win as the favorite

Best odds: -265 at DraftKings

Pittsburgh averages 24 points per game. If the Steelers’ offense can keep scoring points, it should not have a problem winning the game. The Browns have not scored 20 points in a game this year.

So if the connection between Rodgers and DK Metcalf heats up, or if the Steelers score a defensive touchdown, it could be a long day at the office for Browns fans.

Why the Browns could win as the underdog

Best odds: +225 at FanDuel

If the Browns run the ball the way they did in London, and of course, if they force turnovers, they can score an upset. Cleveland’s lone win, 13-10 over the Packers, was a shocker, but it followed that formula.

The Browns defense is a great equalizer, since they are playing extremely well despite the team’s sub-.500 start. This spread could be two-plus-touchdowns — particularly with Pittsburgh’s star-laden defense going against a late-round rookie QB making his first road start in the NFL.

But if Myles Garrett and Co. can get after Rodgers, and Quinshon Judkins and Jerome Ford can combine for 100 yards again, Cleveland would have a real shot.

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